Blood turned into nerve cells by Canadian researchers.
Canadian scientists have discovered a way to turn a simple blood sample from a man or woman into a variety of nerve cells, including those that are responsible for pain, numbness and other sensations. This technology will allow researchers to test potential drugs for treating pain using the nerve cells in a lab, all based on an individual patient's own genetic signature, says Mick Bhatia, who led the team of researchers at McMaster University in Hamilton. Now we can take easy to obtain blood samples and make the main cell types of neurological.
Systems the central nervous system and the peripheral nervous system in a dish that is specialized for each patient. According to Mick Bhatia, Nobody has ever done this with adult blood, ever Up until now, there has been no good way to get access to human neural cells to test or study. While researchers can buy certain kinds of rat neural cell lines, they don't consistently respond the way human neural cells do. The new technique involves extracting stem cells from blood ones that normally have the potential to become red blood cells or various kinds.
Of white blood cells involved in fighting off pathogens. The blood stem cells are converted over about a month into neural stem cells using a patented technique. Those cells can survive for several months in a petri dish. These neural stem cells are then manipulated in the lab to give rise to several types of nerve cells, including those that make up the peripheral nervous system throughout the arms, legs and the rest of the body. We can actually take a patient's blood sample, as routinely performed in a doctor's office,.
And with it we can produce one million sensory neurons. We can also make central nervous system cells. The researchers hope to discover new pain drugs that take aim only at the peripheral nerve system, while not affecting the brain and the rest of the central nervous system. You don't want to feel sleepy or unaware, you just want your pain to go away, says Bhatia. His lab hopes to further develop the bloodgenerated neural stem cells into motor and other kinds of neurons that could conceivably one day be transplanted into patients to restore healthy.
Why Do People Have Blind Spots
This episode was proudly made possible by the allnew 2015 Subaru Legacy. It's not just a sedan, it's a Subaru. Can you see everything on the screen without moving your eyes Look at me did you see that Didn't think so.a Howdy lookers, thanks for tuning into DNews, I'm Trace. Eyes are little 1 inch diameter balls 2.54 cm tucked in your head, and though they're magnificent, human eyes aren't even CLOSE to the best in the animal kingdom. In fact, your brain is tricking you into thinking your eye is seeing things that aren't there RIGHT NOW. We've all got blind spots that.
We can't see, and huge sections of our vision are just wrong! Take a piece of paper with a dot and a plus on it. Close one eye, hold the paper close to your face and look straight at the dot, pulling it away slowly. Eventually, the plus should disappear! That's your blind spot. If you switch eyes, the dot should disappear. You might have to try it a couple of times. To understand WHY this happens, we have to go inside the eye. If you could fly into the pupil and inside the eyeball to look around you'd be floating.
In vitreous humor of the inner eye. It's a clear, gellike material. On the walls of the eye, you'd see blood vessels streaming everywhere, and spread across the back of the eye you'd see the rod and cone cells of the retina. Rods are for low light, cones are for color and visual detail. If you got closer to the retina, you could spot the macula right in the middle with only cone cells that's the only part of your vision that you can see clearly. If you look at my face here, you can see it clearly, but while still looking at my face pay attention.
To the walls around me, or my shirt. It's VERY difficult to comprehend the rest of your visual field. The macula is truly the only point of visual clarity! From there, you could follow the nerves of the retina, like following a bunch of extension cords to the wall. Eventually, you'd get to the optic disk a part of the eye with no rods or cones. That's where the optic nerve enters the eyeball! It's kind of like where your eye plugs in. And it causes a blind spot. There's nothing there for your eye to perceive.
Since there are no rod or cone cells! My eye doctor was nice enough to send me a picture of the inside of my own eye. You can see the macula here, and the optic nerve here. That is my point of clarity, and my blind spot! If it seems stupid to have a blind spot, you're right. Cephalapods don't have one, because their optic nerves run BEHIND the retina rather than in front of it. Think of it this way, cephalopods have their wiring inside the walls, but because of an unfortunate evolutionary.
Mutation, mammals didn't and thus we all have blind spots. The reason you don't see this spot all the time is because your brain fills it in. Try doing the dot and plus experiment with a piece of colorful paper and your brain will fill it in with color. That's your brain tricking you into thinking your vision is perfect, when it's really not. Silly brain, tricks are for nonscientists. Blind spots are very important to be aware of especially when you're driving! That's why we wanna thank Subaru for making this episode possible. And especially the allnew.
Foot Doctor Old Bridge New Jersey Advanced Feet and Ankle Care
Have you recently gotten a sprained foot due to a sports injury Suffering from arthritis, heel pain, or bunions Then Advanced Feet and Ankle Care is your solution! As the premier foot doctor in Old Bridge, we can handle all of you podiatric needs. From xrays and diagnostic exams to orthotics, braces, and physical therapy, Advanced Feet and Ankle Care is here for you. As a member of the American Board of Podiatric Surgery and the American Podiatric Medical Association, you can rest assured that our comprehensive foot and ankle treatments can remedy any foot ailment. Call us today to schedule an appointment.
Blood turned into nerve cells by Canadian researchers 2015 HD
Blood turned into nerve cells by Canadian researchers Mick Bhatia, director of McMaster University's Stem Cell and Cancer Research Institute, says his lab hopes to eventually develop neurons that could one day be transplanted into patients to restore healthy brain cells as a treatment for various diseases, like Alzheimer's. JD HowellMcMaster UniversityCanadian Press Canadian scientists have discovered how to turn a simple blood sample from a man or woman into a variety of nerve cells, including those that are responsible for pain, numbness and other sensations The technology will allow researchers to test potential drugs for treating pain using the nerve cells in a lab, all based on an individual patient's own genetic signature, said Mick Bhatia, who led the team of researchers at McMaster University in Hamilton.
Ow we can take easy to obtain blood samples and make the main cell types of neurological systems the central nervous system and the peripheral nervous system in a dish that is specialized for each patient, said Bhatia, director of McMaster's Stem Cell and Cancer Research Institute. Up until now, there has been no good way to get access to human neural cells to test or study, Bhatia told CBC News. While researchers can buy certain kinds of rat neural cell lines, they don't consistently respond the way human neural cells do.
Peripheral Nervous System Disorders Diagnosis and Treatment
The peripheral nervous system is the part of the nervous system that excludes or is outside of the brain and the spinal cord. We take care of patients that have disorders that affect the motor neurons, which live in the spinal cord the peripheral nerves that extend out into the arms and legs as well as the muscles and the connection between the nerves and the muscles. Some of the disorders that a nerve and muscle a disease specialist will evaluate and develop care plans for include muscle disorders such as muscular dystrophy,.
Polymyositis, dermatomyositis, peripheral neuropathies such as Charcot Marie Tooth disease or hereditary neuropathy and as well as the neuromuscular junction disorders such as myasthenia gravis. Some symptoms that can be associated with the peripheral nervous system include generalized weakness, fatigue, numbness, tingling, sometimes pain can be caused by disorders of the peripheral nerve. The evaluation of a patient with a possible peripheral nervous system disorder first begins with the very careful history to understand how the symptoms started and how they affect the patient. From the history we extend to the physical exam,.
Spine Academy Diagnostic Testing and Back Pain Treatment
As part of Orthopedic Associates of Central Maryland, the Spine Academy focuses on finding the cause of your neck or back pain and determining the best course of treatment. There are different areas where a nerve can be pinched. So if you're having pain coming down to your hand, it just doesn't have to be coming from a pinched nerve in your neck. It can be up in your elbow. It can be at your wrist. So it's really important for the doctor to really thoroughly examine you in addition to listen to what can provoke your symptoms.
Before making a real accurate diagnosis. Our thorough evaluation of your condition may include advanced diagnostic tests, such as our onsite electromyography, EMG, nerve testing to ensure we know the origin and extent of any spinal injury. It's a test that looks first to see how the peripheral nerves, or the nerves in your arms or legs, how well they're conducting electrical signal. And that's compared to a set of normal values. The next part, the actual needle portion, which is the true electromyography proportion, looks to see if there's any damage from the nerve to the muscle. And that gives us an.
Idea of where the nerve is damaged. Is it damaged higher up in your neck or back Or is it being damaged at more common places peripherally, such as your wrist, your elbow, or on the harder part of your knee Primarily, you're looking at it for carpal tunnel versus a pinched nerve in your neck. A couple other locations where it tries to determine is whether or not it's a pinched nerve at your elbow versus a neck. Is it a pinched nerve at the outer part of your knee.
Versus your low back Or if it's your low back versus something called a tarsal tunnel syndrome, which is a nerve at the middle part of your ankle. Those are the primary reasons to be getting an EMG nerve conduction study. Our goal is to speed your recovery, eliminate your pain, and to maximize your function. We diagnose and treat conditions of the lower back, lumbar spine and SI joint, upper back, thoracic spine, and neck, cervical spine. Call 4106441880 or request an appointment online for superior service and quality care.
Musculocutaneous Nerve Innervation Anatomy Human Anatomy Kenhub
Hello, everyone! This is Matt from Kenhub, and in this tutorial, we will discuss the anatomy and innervation of the musculocutaneous nerve. The musculocutaneous nerve is a major peripheral nerve in the upper arm. It supplies the biceps brachii the brachialis and the coracobrachialis. The lateral cutaneous nerve, which supplies the skin on the lateral aspect of the forearm, arises from the musculocutaneous nerve. The musculocutaneous nerve originates in the lateral cord of the brachial plexus. It starts in the axilla and cuts through the coracobrachialis muscle near its insertion point on the humerus.
It continues anterior to the brachialis and dorsal to the biceps brachii, serving as innervation for all these muscles. The musculocutaneous nerve emerges laterally to the biceps tendon where it gives rise to the lateral cutaneous nerve, which supplies the skin on the lateral aspect of the forearm. It is of interest to know that the musculocutaneous nerve can have a varied anatomical course, and it often adheres to the median nerve and interacts with it. This tutorial is more fun than reading a textbook, right If you want more tutorials, interactive.
Radial Nerve Anatomy, Innervation Distribution Human Anatomy Kenhub
Hello again, everyone. This is Matt from Kenhub! And in this short tutorial, we will discuss the anatomy, innervation, and distribution of the radial nerve. The radial nerve serves as nerve supply for some muscles of the upper arm and most of the extensors of the forearm. This nerve is the direct continuation of the posterior cord of the brachial plexus. It courses between the brachioradialis and the brachialis to the elbow where it divides into a deep branch and a superficial branch at the level of the radial head. The superficial branch uses the brachioradialis as a guiding structure to reach the wrist.
Joint and arrives at the dorsum of the hand. In contrast, the deep branch penetrates the supinator muscle and continues to the extensors of the forearm. It is important to note that the branches supplying the brachioradialis and extensor carpi radialis longus branch off before the division of the radial nerve, whereas the nerve supplying the extensor carpi radialis brevis, the posterior interosseus nerve arises just after the division. The radial muscles this nerve supplies are the brachioradialis muscle, the extensor carpi radialis longus, and the extensor carpi radialis brevis. The radial musculature supports movements.
Of the elbow, hand, and radioulnar joints. The brachioradialis is mainly responsible for the lateral contour of the elbow and forearm. The extensor carpi radialis longus and the extensor carpi radialis brevis function as the dorsal extensors and the radial abductors of the wrist joint. They also contribute to a strong fist closure by stretching the flexor muscles of the hand and fingers prior to contraction. This tutorial is more fun than reading a text book, right If you want more tutorials, interactive quizzes, articles, and an atlas of human anatomy, click on the Take me to Kenhub button.
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